Health Universe, a San Francisco, California-based company that provides an AI platform for automating complex healthcare workflows, has raised $6 million in seed funding led by Kleiner Perkins.
The funding brings the company’s total raised to $9.5 million, following a pre-seed round backed by Susa Ventures, Twelve Below, and Oncology Ventures.
The company intends to use the funds to support its expansion across AMCs and deepen integrations with oncology and clinical research teams.
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Healthcare organizations are facing growing pressure from clinician burnout, heavy administrative workloads, and long clinical trial timelines, which can take nearly 8 months to enroll a single patient. While AI has shown promise, many tools act as “black boxes,” making them hard to audit and use safely in critical clinical settings. Health Universe addresses this by offering a secure compliant platform that enables organizations to deploy transparent, auditable AI agents. In less than a year since launching Navigator, the platform has processed over 170 million clinical documents.
Health Universe works as an AI workflow engine, allowing healthcare organizations to build, deploy, and manage both autonomous and human-in-the-loop agents in a secure, ONC-certified, and HIPAA-compliant environment. Its platform includes:
- Navigator: A secure workspace to deploy, manage, and monitor AI agents working on patient records. It can pull data from TEFCA, FHIR, or uploads, and supports ready-made, custom, and third-party agents.
- Explorer: A workspace for building patient groups and running agents at a population level.
- Observer: Tracks agent performance, including cost, errors, and high-risk issues.
- Oncology Agents: Turn complex medical records into structured summaries, including key details such as diagnosis, treatment history, and disease progression, reducing review time from hours to minutes. Used by leading oncology practices, and New York Cancer and Blood Specialists.
- Clinical Trials Agents: A system that turns short study summaries into full clinical trial protocols, including automated submissions and workflow integration, developed with Duke Clinical Research Institute.
The company is also building an Agent-to-Agent (A2A) Marketplace to connect healthcare AI agents, enabling them to share data and collaborate across organizations securely.
Early results show a strong impact. At Duke Clinical Research Institute, Health Universe’s Project Loom has sped up clinical trial setup by 30–40 times, reducing timelines from six to nine months to about a week, while saving 93% of time on key tasks and making document processing 10 times faster.
Health Universe also stands out for its strong focus on compliance and regulation. It is ONC B.11 certified, part of the TEFCA network, SOC 2 Type II compliant, and fully HIPAA-aligned—standards that often take competitors over a year to achieve. In competitive evaluations, including at Duke, the company has outperformed larger tech providers with its flexibility, ease of use, and strong governance.
“Healthcare doesn’t need another chatbot,” said Dan Caron, Founder and CEO of Health Universe. “It needs AI systems that are traceable, compliant, and designed for real clinical workflows. Our platform lets organizations deploy agents to solve key use cases in days or weeks rather than months or years, while providing the security, transparency, and auditability that hospitals, and healthcare institutions require. This new funding will help us expand these capabilities and bring trusted AI agents to more health systems nationwide.”
“AI is already changing healthcare, but trust, security, and compliance are essential,” said Annie Case of Kleiner Perkins. “Health Universe combines technical expertise with regulatory readiness making it a leader in bringing AI agents safely into academic medicine.”
About Health Universe
Founded by Dan Caron and Doug Fridsma, Health Universe is headquartered in San Francisco and backed by Kleiner Perkins, Susa Ventures, Twelve Below, and Oncology Ventures. The company provides AI infrastructure that lets healthcare organizations safely deploy and manage autonomous and human-in-the-loop agents in regulated clinical settings. Its HIPAA-compliant platform, designed for academic medical centers, health systems, and life sciences organizations, automates complex workflows across oncology, clinical research, and healthcare operations, reducing manual hours to minutes. Internal AI teams can also use Health Universe to build, and launch applications and agents quickly in a secure, compliant environment.
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