Trase Raises $107M in Seed Funding Led by ARCH Venture Partners
Jun 26, 2026 | By Startuprise io

Trase, a McLean, Virginia-based developer of an agentic operating system and artificial intelligence agents for high-stakes environments, has raised $107 million in a seed funding round led by ARCH Venture Partners.
The round also saw participation from Red Cell Partners and other strategic technology investors.
The company plans to use the funding to grow its corporate sales teams, expand its engineering team, and speed up development of its proprietary operating system, Trase Origin.
Trase is an AI platform that provides an operating system and AI agents for high-stakes industries. It offers hundreds of ready-to-use agents that can be deployed in weeks instead of months across different sectors. The platform includes built-in compliance and governance features, helping organizations automate workflows, improve performance, and create business value.
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Since launching last fall, Trase has been working with Duke University Health System to deploy AI agents in its Division of Cardiology. One key use case is automating the processing of more than 5,000 faxes the clinic receives each month, a task that was previously handled manually by medical assistants and nurses. Peer-reviewed research on the deployment is expected soon. Early results show that Trase's AI routing system is already improving workflow efficiency.
Trase's fax routing agent is part of a larger set of AI agents being deployed at Duke. These agents help automate administrative work and support tasks such as chronic disease management. All Trase agents are designed for high-stakes environments. They include built-in data protection, human feedback learning, audit trails, and safeguards that ensure important decisions are made by people when needed.
“We’re honored to welcome Bob Nelsen and ARCH to the team,” said Verstandig, CEO and Co-Founder of Trase. “In the age of AI, powered by the sovereignty, predictability, and trustworthiness that Trase’s OS delivers, agents are handling the onerous, immutable tasks that bog down highly trained individuals. Shifting that valuable mental capacity to higher-acuity work will help make the most important systems in the United States cheaper, faster, and better for every American.”
“We used to show up on Monday mornings to hundreds of faxes waiting to be routed. When we first turned on the Trase fax routing agent, it processed the lion's share of them by the end of the day. It liberated our team to focus on the work they actually trained for and enjoy doing,” said Manesh Patel, MD, Chief of the Division of Cardiology at Duke Health. “This work with Trase has shown us that the promise of AI in a clinical setting is real.”
"Regulated industries are full of brilliant people who can exponentially serve their country and their customers through the power of AI. Trase delivers that boost to augment capabilities," said Robert Nelsen, co-founder and Managing Director of ARCH Venture Partners. “Grant has built the right team, the right technology, and has proven it works in industries that are the most demanding for performance.”
About Trase
Founded in 2023 by Grant Verstandig and Joe Laws, Trase is an AI operating system for industries where security, compliance, and reliability are critical. The platform is HIPAA and SOC 2 compliant and allows organizations to deploy AI agents across cloud, on premises and edge environments. It also provides policy enforcement, continuous monitoring and detailed audit trails to ensure AI operates safely and securely.
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